| Overall | Pct | Streak | Conf. | Pct | 6-13 | .316 | L1 | 2-10 | .167 |
| Date | Opponent | Location | Coverage | Time/Result | | Sep. 11, 2021 | @ Wingate Invitational - Day 1 | Wingate,NC | | | Recap | Box | | Sep. 12, 2021 | @ Wingate Invitational - Day 2 | Wingate,NC | | | Recap | Box | | Sep. 18, 2021 | @ North Greenville | Tigerville,SC | | 6-1 W | Recap | Box | | Oct. 23, 2021 | CONVERSE | SALISBURY | | 3-4 L | Recap | Box | | Feb. 6, 2022 | ANDERSON* | SALISBURY | | 0-7 L | Recap | Box | | Feb. 10, 2022 | @ Erskine | Due West,SC | | 2-5 L | Recap | Box | | Feb. 11, 2022 | BELMONT ABBEY | SALISBURY | | 5-2 W | Recap | Box | | Feb. 19, 2022 | @ Francis Marion | Florence,SC | | 1-6 L | Recap | Box | | Feb. 26, 2022 | LEES-McRAE | SALISBURY | | 4-3 W | Recap | Box | | Mar. 6, 2022 | MARS HILL* | SALISBURY | | 2-5 L | Recap | Box | | Mar. 13, 2022 | @ JC Smith | Charlotte,NC | | 5-2 W | Recap | Box | | Mar. 15, 2022 | LIMESTONE* | SALISBURY | | 1-6 L | Recap | Box | | Mar. 18, 2022 | LENOIR-RHYNE* | SALISBURY | | 1-6 L | Recap | Box | | Mar. 24, 2022 | @ Lincoln Memorial* | Harrogate,TN | | 1-6 L | Recap | Box | | Apr. 2, 2022 | @ Tusculum* | Greeneville,TN | | 1-6 L | Recap | Box | | Apr. 4, 2022 | @ Queens* | Charlotte,NC | | 1-6 L | Recap | Box | | Apr. 9, 2022 | NEWBERRY (SENIOR DAY)* | SALISBURY | | 2-5 L | Recap | Box | | Apr. 12, 2022 | @ Coker* | Hartsville,SC | | 5-2 W | Recap | Box | | Apr. 13, 2022 | WINGATE* | SALISBURY | | 1-6 L | Recap | Box | | Apr. 14, 2022 | @ UVA Wise* | Wise,VA | | 4-3 W | Recap | Box | | Apr. 16, 2022 | @ Carson-Newman* | Jefferson City,TN | | 0-7 L | Recap | Box |
Home dates are in bold.
* - indicates South Atlantic Conference event
All times are local.
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